Mississippi River

1. 1

   Lake Itasca

   headwaters of the river · reached via Itasca State Park
2. 2
   Itasca State Park

   oldest and largest Minnesota state park · on US Route 71
3. 3

   St. Cloud, Minnesota

   along US 10 heading southeast
4. 4

   Minneapolis-St. Paul (Twin Cities)

   start of navigable waters on the river · US 10 and I-94 follow opposite riverbanks here
5. 5
   Hastings, Minnesota

   US 61 branches south from US 10 here
6. 6
   Prescott, Wisconsin

   bridge crossing point opposite Hastings
7. 7
   La Crosse, Wisconsin

   river forms Minnesota-Wisconsin border here
8. 8
   Dubuque, Iowa

   at Iowa's border with Wisconsin and Illinois
9. 9

   Quad Cities

   straddles a state line following the river · caution advised for night travel on foot
10. 10
    Hannibal, Missouri

    associated with Mark Twain's fiction
11. 11
    St. Louis, Missouri

    Gateway Arch landmark · junction with Route 66 and other itineraries · east side (East St. Louis, Illinois) flagged as higher-crime
12. 12
    Memphis, Tennessee

    on Tennessee's border with Arkansas · noted as an Elvis pilgrimage destination
13. 13

    Mississippi Delta region

    historic blues and juke-joint area · riverboat casinos along this stretch
14. 14
    Greenville, Mississippi

    river forms the Arkansas-Mississippi state border near here
15. 15
    Vicksburg, Mississippi

    site of an 1863 Civil War siege · US Army Corps of Engineers district for river charts
16. 16
    Baton Rouge, Louisiana

    Louisiana state capital · river becomes the Louisiana-Mississippi border before this point
17. 17
    New Orleans, Louisiana

    major seaport · route terminus
18. 18

    Mississippi River Delta / Gulf of Mexico

    river terminates here beyond New Orleans

• Lower Mississippi Historic Scenic Byway
• Great River Road
• Great River Road - Missouri

Lookouts along this trip

Scenic overlooks on the official byways this route runs along, in drive order. Each byway’s own page carries its full list.

Named places along this route

Typed places from the atlas within thirty miles of this trip, measured to its own snapped line. Each one traces to its source record, and each one lists the byways near it in return.